Endocrine Abstracts

IntroductionGrowth retardation (GR) is a frequent complaint in pediatrics. A clear and rapid diagnostic process is essential in order to improve the prognosis for height. The aim of our study was to review the epidemiological, clinical and etiological aspects of GR and to assess the height gain particularly after treatment for Growth hormone (GH) deficiency.MethodologyThis is a retrospective study of 27 consu...

Background: Primary hyperparathyroidism is a common endocrine disorder characterized by hypercalcemia, resulting from excessive secretion of parathyroid hormone. Parathyroidectomy, is considered as the definitive treatment for this condition, leading in most cases to remission and resolution of hypercalcemia. However, some patients experience surgical failure. Persistent hyperparathyroidism is defined as persistence of hypercalcemia after parathyroidectomy or recurrence of hyp...

Background: Primary hyperparathyroidism, is defined by hypercalcemia associated with an elevated or inappropriately normal parathyroid hormone(PTH) levels stemming from hyperfunctioning parathyroid glands. It’s a prevalent endocrine disorder. Parathyroidectomy, the surgical excision of affected glands, stands as the definitive treatment, typically resulting in remission and normalization of calcium levels. However, persistent elevation of serum PTH post-parathyroidectomy ...

Introduction: Wilson’s disease is a rare and serious genetic disorder. The accumulation of copper in glands causes several endocrine pathologies. Herein, we report a rare case of hypophysitis with corticotropic deficiency caused by Wilson’s disease.Observation: A 33-years-old female patient was referred to the endocrinology department for hypoglycemia. She had a history of Wilson’s disease diagnosed at the age of nine complicated by cirrho...

Introduction: Isolated hypogonadotropic hypogonadism is a heterogeneous group of genetic abnormalities affecting the hypothalamic pituitary gonadal axis. The main mechanism consists of an impairment of the production or the action of gonadotropin releasing hormone (GnRH). While several mutations have been identified, the majority of cases remain without etiology. The objective of our study was to describe the clinical and biological profiles of these diseases.<p class="abs...

Introduction: Thyroid eye disease (TED) is an autoimmune inflammatory disorder affecting the orbital tissues. It occurs with thyroid dysfunction notably Graves’ disease. TED exhibits different severity patterns and has a lot of risk factors. We, herein, report a rare case of a severe TED developing after COVID-19 infection in a patient initially treated for hyperthyroidism without ocular manifestations.Observation: A 48-year-old female with a histor...

Introduction: Subclinical hyperthyroidism (SH) is defined by normal thyroid hormone levels and reduced thyroid-stimulating hormone (TSH) concentration. It still raises intriguing questions about its clinical impact, management and outcomes. The aim of our study was to determine the underlying etiologies of SH, its clinical features and its outcomes in Tunisian patients.Methods: We conducted a retrospective study at Charles Nicolle Hospital, including 46 ...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine pathology in women with a high prevalence varying between 5 and 20%. Autoimmune thyroid diseases (AITD) are the most prevalent organ-specific autoimmune diseases, particularly in young women. The purpose of our study was to determine the prevalence of AITD in a group of patients with PCOS compared to a control group.Patients and Methods: 103 women were recruited into the study, aged bet...

Introduction: Pheochromocytomas are rare catecholamine-secreting tumors presenting with various clinical manifestations. Hypertension is the most common finding in pheochromocytomas. It can be either persistent or paroxysmal. Study Design: We conducted a retrospective study of 34 patients who were admitted into the endocrinology department of Charles Nicolle hospital, with a diagnosis of a pheochromocytoma from January 2005 to November 2022.Results: Twen...

Introduction: Pheochromocytomas are rare, mostly benign catecholamine-producing neuroendocrine tumors. Clinical manifestations are heterogenous, including persistent or paroxysmal hypertension, sweating, palpitation and headaches known as Menard triad. Diagnostic approach is based on demonstration of catecholamine excess and tumor localization. Our study aimed to describe clinico-biological and radiological features of pheochromocytomas.Methods: We condu...